The automotive industry depends on thousands of components working together to deliver safety, comfort, durability, and reliable performance. While engines, transmissions, and electronic systems often receive the most attention, rubber seals and gaskets play an equally important role in everyday vehicle operation.
From keeping rainwater outside the cabin to reducing wind noise and protecting sensitive components, automotive sealing systems are essential to vehicle quality. Traditionally, many of these applications have relied on conventional rubber materials such as EPDM. Today, thermoplastic elastomers (TPE) and thermoplastic vulcanizates (TPV), including Santoprene™, offer manufacturers additional material and processing options.
Santoprene™ TPV seals and gaskets combine rubber-like flexibility with thermoplastic processing advantages, making them suitable for a variety of automotive sealing and extrusion applications.
For automotive OEMs, component manufacturers, and engineering teams, understanding where these materials fit can help improve product design, manufacturing efficiency, and long-term component performance.
What Are Santoprene™ TPV and TPE Automotive Seals?
Santoprene™ is a thermoplastic vulcanizate (TPV) material supplied by Celanese. TPVs belong to the broader family of thermoplastic elastomers, which are designed to provide elastic properties similar to rubber while allowing processing through thermoplastic manufacturing methods.
Unlike conventional vulcanized rubber, thermoplastic elastomers can be processed using techniques such as extrusion and injection molding, depending on the material grade and component design.
In automotive applications, Santoprene™ TPV can be used to manufacture flexible sealing profiles, weatherstripping, gaskets, and other custom rubber components.
The material’s combination of flexibility, sealing performance, weather resistance, and aging characteristics makes it useful for applications exposed to changing environmental conditions.
SantopSeal manufactures custom extruded rubber seals and gaskets using Santoprene™ TPV and other materials, including TPE, EPDM, neoprene, and silicone. Its capabilities include custom profile extrusion, cut-to-length products, vulcanized splicing, and adhesive application.
Why Thermoplastic Rubber Seals are Important in the Automotive Industry?
Automotive seals are not simply rubber strips placed between two surfaces. Their shape, hardness, compression behaviour, and material properties influence how effectively they perform throughout a vehicle’s service life.
A door seal, for example, must compress sufficiently when the door closes while maintaining enough resilience to provide a reliable barrier against water, dust, and outside noise.
Similarly, a glass run channel must support window movement while maintaining contact with the glass and helping prevent unwanted water entry.
These requirements make material selection and profile design critical.
Thermoplastic rubber materials such as Santoprene™ TPV provide manufacturers with options for designing custom sealing profiles with specific dimensions, hardness levels, and functional characteristics.
7 Major Automotive Applications of Santoprene™ TPV Seals and Gaskets

- Automotive Door Seals and Weatherstripping
Door seals are among the most recognizable applications of automotive rubber extrusion.
They create a barrier between the vehicle door and body, helping prevent water, dust, and air from entering the passenger compartment.
A properly designed door seal also contributes to cabin comfort by helping reduce wind noise and vibration.
Santoprene™ TPV can be extruded into custom solid or hollow profiles designed around the vehicle’s sealing requirements.
Depending on the application, manufacturers may use D-shaped, P-shaped, bulb, or other custom profiles to achieve the required compression and sealing contact.
- Automotive Window Seals and Glass Run Channels
Vehicle windows require specialized sealing systems because they must move while remaining protected from environmental exposure.
Glass run channels guide the window during opening and closing while helping maintain a seal around the glass.
These components must accommodate repeated movement, changing temperatures, and exposure to moisture.
Custom TPE and TPV extrusions can be designed for specific channel geometries, installation methods, and sealing requirements.
For automotive manufacturers, selecting the appropriate profile helps balance window movement, sealing contact, and component durability.
- Tailgate, Trunk, and Roofline Seals
Rear closures and roofline areas are exposed to rainwater, dust, sunlight, and temperature fluctuations.
Tailgate and trunk seals help protect luggage compartments and vehicle interiors from unwanted water and environmental exposure.
Roofline seals and rocker panel seals serve similar protective functions in their respective locations.
Santoprene™ TPV extrusions can be manufactured in customized shapes and lengths to accommodate different vehicle designs.
For these applications, the profile must fit accurately and maintain suitable sealing contact across the intended installation area.
- Automotive Gaskets for Component Protection
Automotive gaskets are used wherever two surfaces require a protective sealing interface.
Their purpose varies depending on the component, but common requirements include preventing moisture ingress, reducing vibration, and maintaining a consistent fit between adjoining surfaces.
TPV and TPE gasket profiles can be manufactured in different hardness levels and geometries to meet specific design requirements.
SantopSeal offers custom extruded gasket profiles, including solid and hollow shapes, as well as cut-to-length and spliced configurations.
The appropriate material should always be selected according to the operating temperature, chemical exposure, compression requirements, and relevant OEM specifications.
- Weather-Resistant Seals for Exterior Automotive Components
Automotive exterior components experience continuous environmental exposure.
UV radiation, rain, temperature changes, and airborne contaminants can affect the performance of sealing materials over time.
Weather-resistant thermoplastic rubber compounds are therefore useful in applications requiring long-term environmental protection.
Santoprene™ TPV offers weather and aging characteristics that make suitable grades relevant for selected exterior sealing applications.
UV-resistant grades may also be considered where the component’s exposure conditions require additional protection.
Material selection should be based on the actual environment and the manufacturer’s technical specifications rather than assuming every TPV grade provides identical performance.
Not every automotive sealing requirement can be addressed using a standard rubber profile.
Different vehicle platforms, body geometries, and component assemblies often require specific cross-sectional shapes.
Custom rubber extrusion allows manufacturers to produce profiles that match the intended installation space and functional requirements.
Common profile configurations include:
- D-shaped rubber seals
- P-shaped gaskets
- Hollow bulb seals
- U-channel and J-channel profiles
- T-shaped strips
- Solid and hollow custom extrusions
- Edge guards and protective profiles
These profiles can be designed around the required dimensions, material hardness, and installation method.
SantopSeal provides custom rubber extrusion services for customers requiring standard or specialized sealing configurations.
- Protective Seals for Automotive Electrical and Electronic Components
Modern vehicles contain electrical systems and electronic assemblies that require protection from environmental exposure.
Depending on the design, rubber seals and gaskets may be used around enclosures, access panels, cable openings, and other interfaces.
The purpose is to help maintain the intended barrier against moisture, dust, and other external conditions.
Thermoplastic rubber materials may be suitable for selected applications where flexibility, sealing properties, and custom extrusion are required.
For electrical applications, engineers should also evaluate electrical properties, flame-retardant requirements, temperature exposure, and applicable OEM standards.
Key Benefits of Santoprene™ TPV for Automotive Seals and Gaskets
The value of Santoprene™ TPV comes from its combination of material performance and manufacturing flexibility.
- Excellent Sealing Properties
- Flexibility and Fatigue Resistance
- Weather and Aging Resistance
- Oil and Chemical Resistance
- Lightweight Material Options
- Flexible Manufacturing and Customization
Automotive OEM Specifications and Material Selection
Automotive manufacturers frequently require sealing materials to comply with defined material and performance specifications.
These requirements may address properties such as hardness, aging, compression behavior, environmental resistance, and other application-specific characteristics.
SantopSeal identifies several automotive specification references associated with available Santoprene™ grades, including:
- Chrysler MS-AR-100 series
- Ford WSD-M2D378 and related specifications
- GM GMW15813 series
The exact specification and approved material grade must be verified for the intended application. A reference to an automotive specification should not be interpreted as automatic approval of every profile or compound.
For OEM projects, engineering teams should confirm the applicable material documentation, testing requirements, and approval process before production.
Preapproval for automotive certification and automotive specs – Please see below list of preapproved TPV Material for various Automotive Product Specifications including major OEMs
- Ford Automotive Product Specification
| WSS-M2D380-B1 | SANTOPRENE 121-73W175 |
| WSS-M2D281-B1 | SANTOPRENE 121-80 |
| WSD-M2D378-A1 | SANTOPRENE 101-55 |
| WSD-M2D379-A1 | SANTOPRENE 101-64 |
| WSD-M2D380-A1 | SANTOPRENE 101-73 |
| WSD-M2D381-A1 | SANTOPRENE 101-80 |
| WSD-M2D382-A1 | SANTOPRENE 101-87 |
| WSD-M2D441-A | SANTOPRENE 103-40 |
| WSD-M2D378-A4* | SANTOPRENE 111-35 |
| WSD-M2D378-A4 | SANTOPRENE 111-45 |
| WSS-M2D278-B1 | SANTOPRENE 121-58W175 |
| WSS-M2D379-B1 | SANTOPRENE 121-67W175 |
| MCDCC JA6A WSS-M9P14-A1 | SANTOPRENE 121-73W175J |
| WSS-M2D282-B1 | SANTOPRENE 121-87 |
| WSD-M2D378-A1 | SANTOPRENE 201-55 |
| WSD-M2D379-A1 | SANTOPRENE 201-64 |
| WSD-M2D380-A1 | SANTOPRENE 201-73 |
| WSD-M2D381-A1 | SANTOPRENE 201-80 |
| WSD-M2D382-A1 | SANTOPRENE 201-87 |
| WSD-M2D378-A4 | SANTOPRENE 211-45 |
| WSS-M2D510-A5 | SANTOPRENE 8221-55M300 |
| WSS-M2D510-A6 | SANTOPRENE 8221-65M300 |
| WSS-M2D510-A7 | SANTOPRENE 8221-75M300 |
| WSS-M2D510-A8 | SANTOPRENE 8221-85M300 |
- GM Automotive product specification approved Santoprene TPV
| GM | Product Or Grade |
| GMW15813P-TPV-(EPDM+PP)-Type 4 | SANTOPRENE 101-55 |
| GMW15813P-TPV-(EPDM+PP)-Type 5 | SANTOPRENE 101-64 |
| GMW15813P-TPV-(EPDM+PP)-Type 6 | SANTOPRENE 101-73 |
| GMW15813P-TPV-(EPDM+PP)-Type 7 | SANTOPRENE 101-80 |
| GMW15813P-TPV-(EPDM+PP)-Type 8 | SANTOPRENE 101-87 |
| GMW15813P-TPV-(EPDM+PP)-Type 2 | SANTOPRENE 111-35 |
| GMW15812P-TPV(EPDM+PP)-Type 4M | SANTOPRENE 121-50M100 |
| GMW15812P-TPV(EPDM+PP)-Type 5M | SANTOPRENE 121-60M200 |
| GMW15812P-TPV(EPDM+PP)-Type 5M | SANTOPRENE 121-62M100 |
| GMW15812P-TPV(EPDM+PP)-Type 7M | SANTOPRENE 121-75M100 |
| GMW15812P-TPV(EPDM+PP)-Type 8E | SANTOPRENE 121-87 |
| GMW15812P-TPV(EPDM+PP)-Type 5E | SANTOPRENE 121-67W175 |
| GMW15825P-TPV(EPDM + PP) Type 5 | SANTOPRENE 121-70B230 |
| GMW15825P-TPV(EPDM + PP) Type 5 | SANTOPRENE 121-70B265 |
| GMW15812P-TPV(EPDM+PP)-Type 6E | SANTOPRENE 121-73W175 |
| GMW15812P-TPV(EPDM+PP)-Type 7M | SANTOPRENE 121-75M200 |
| GMW15812P-TPV(EPDM+PP)-Type 7E | SANTOPRENE 121-80 |
| GMW15825P-TPV(EPDM+PP)-Type-6 | SANTOPRENE 121-80B265 |
| GMW15812P-TPV(EPDM+PP)-Type 7E | SANTOPRENE 121-80W175 |
| GMW15812P-TPV(EPDM+PP)-Type 8M | SANTOPRENE 121-85M100 |
| GMW15812P-TPV(EPDM+PP)-Type 9 | SANTOPRENE 123-40 |
| GMW15812P-TPV(EPDM+PP)-Type 10E | SANTOPRENE 123-50W175 |
| GMW15813P-TPV-(EPDM+PP)-Type 4 | SANTOPRENE 201-55 |
| GMW15816P-TPV (EPDM+PP) Type 4 | SANTOPRENE 8221-55M300 |
| GMW15816P-TPV (EPDM+PP) Type 5 | SANTOPRENE 8221-65M300 |
| GMW15816P-TPV (EPDM+PP) Type 6 | SANTOPRENE 8221-75M300 |
| GMW15812P-TPV(EPDM+PP)-Type 4E | SANTOPRENE 121-58W175 |
| GMW15813P-TPV-(EPDM+PP)-Type 10 | SANTOPRENE 103-50 |
| GMW15813P-TPV-(EPDM+PP)-Type 9 | SANTOPRENE 103-40 |
Santoprene™ TPV vs. Traditional EPDM Rubber: What Should Automotive Manufacturers Consider?
EPDM remains widely used in automotive weatherstripping and sealing applications. Santoprene™ TPV provides an alternative material option for applications where thermoplastic processing and specific performance characteristics are desirable.
Neither material is universally suitable for every automotive component. Selection should depend on the application and the required performance specifications.
| Comparison Factor | Santoprene™ TPV | EPDM Rubber |
| Material family | Thermoplastic vulcanizate | Conventional synthetic rubber |
| Processing | Thermoplastic extrusion and molding | Commonly processed through rubber manufacturing and vulcanization |
| Automotive applications | Custom seals, gaskets, weatherstripping | Weatherstripping, seals, gaskets |
| Flexibility | Available in different hardness grades | Available in different compound formulations |
| Weather resistance | Grade-dependent | Generally valued for weather and ozone resistance |
| Custom profiles | Suitable for custom extrusion | Suitable for custom rubber extrusion |
| Material selection | Based on TPV grade and application | Based on EPDM compound and application |
The most appropriate choice depends on the vehicle manufacturer’s specifications, production process, service environment, and total component requirements.
Why Choose Custom Santoprene™ TPV Extrusion for Automotive Applications?
A sealing component is only effective when its material and geometry work together.
Custom extrusion allows automotive manufacturers to develop profiles that fit their specific assembly requirements rather than adapting the design around a generic rubber strip.
SantopSeal supports custom rubber extrusion projects with services that include:
Custom profile extrusion: Manufacturing profiles according to customer drawings, dimensions, and requirements.
Continuous or cut-to-length production: Supplying extruded seals in continuous lengths or specified cut lengths.
Vulcanized splicing: Joining profile ends where the application requires a continuous or formed gasket.
Adhesive application: Providing pressure-sensitive or heat-activated adhesive options where specified.
Custom packaging and private labeling: Supporting customer-specific packaging and product identification requirements.
These capabilities help automotive component manufacturers source sealing products that align with their production and assembly needs.
Frequently Asked Questions About Santoprene™ TPV Automotive Seals
What is Santoprene™ TPV used for in the automotive industry?
Santoprene™ TPV is used in selected automotive sealing and extrusion applications, including door seals, weatherstripping, gaskets, glass run channels, and custom protective profiles.
Are Santoprene™ TPV seals suitable for automotive weatherstripping?
Suitable Santoprene™ TPV grades can be used for automotive weatherstripping applications. The appropriate grade and profile should be selected according to environmental exposure, compression requirements, and OEM specifications.
What is the difference between TPE and TPV automotive seals?
TPE is the broader family of thermoplastic elastomers. TPV is a specific type of TPE with a vulcanized rubber phase dispersed within a thermoplastic matrix. Santoprene™ is a TPV material.
Can Santoprene™ TPV gaskets be custom extruded?
Yes. SantopSeal manufactures custom extruded TPV and TPE gaskets in different shapes, sizes, and hardness levels according to customer requirements.
What hardness options are available for Santoprene™ TPV seals?
SantopSeal lists rubber gasket and seal options with durometer hardness ranging from 40 Shore A to 90 Shore A, subject to material selection and application requirements.
Are Santoprene™ TPV seals resistant to outdoor weather conditions?
Santoprene™ TPV offers weather and aging characteristics suitable for selected outdoor applications. UV-resistant grades are also available. The exact performance depends on the selected grade and exposure conditions.
Does SantopSeal manufacture automotive rubber seals to OEM specifications?
SantopSeal offers custom extruded seals and gaskets using Santoprene™ TPV grades associated with various automotive specifications. Customers should confirm the exact grade, documentation, and approval requirements for their application.
Conclusion: Custom Santoprene™ TPV Seals for Automotive Performance
Automotive sealing systems have a direct impact on vehicle protection, comfort, and component reliability. From door weatherstripping and glass run channels to custom gaskets and exterior protective profiles, the right rubber material helps manufacturers meet demanding design requirements.
Santoprene™ TPV provides a combination of rubber-like flexibility, sealing performance, weather resistance, and thermoplastic processing advantages for selected automotive applications.
However, material selection is only one part of the equation. Profile geometry, hardness, manufacturing tolerances, installation method, and OEM requirements all influence the final result.
SantopSeal specializes in custom Santoprene™ TPV, TPE, and other rubber extrusions for automotive and industrial applications. With custom profile development, cut-to-length production, splicing, and adhesive application capabilities, SantopSeal helps manufacturers source sealing components tailored to their requirements.
For automotive OEM suppliers and component manufacturers looking for custom thermoplastic rubber seals and gaskets, SantopSeal offers product selection and design support from initial requirements through finished extrusion. Contact SantopSeal at info@santopseal.com or call 412-444-1888.

